Italia.it describes the Tremezzina as the area around Tremezzo, one of the lake's main tourist destinations, with a mild climate sheltered by the mountains from cold air. Since 25 May 2014 it has also been the name of a single municipality, joining Tremezzo, Lenno, Mezzegra and Ossuccio, so a visit here can take in several villages in one stretch of shore.
That shoreline is best taken slowly. The Greenway del Lago di Como passes through the whole municipality, past churches, historic palaces, Villa Carlotta and the Tremezzo boat dock, and the boats of Navigazione Laghi call at Tremezzo, Lenno and Villa Carlotta. You can walk one stretch and take the boat back, which makes this one of the easiest parts of the lake to explore without a car.